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Peritoneal mesothelioma is a form of cancer that affects the lining of the abdomen (the peritoneum). It is caused by the ingestion of asbestos fibers. What is Peritoneal Mesothelioma? Peritoneal mesothelioma accounts for 20 to 25 percent of all mesothelioma cases. It is the most common diagnosis after pleural mesothelioma. Peritoneal patients have longer life expectancies than those with other types of mesothelioma. Some studies report patients living upwards of 5 years after cytoreductive surgery. How Is Peritoneal Mesothelioma Treated? Peritoneal Mesothelioma Icon Cytoreductive Surgery This is the only surgical option available to those with a peritoneal diagnosis. This surgery has high success rates when it is combined with chemotherapy. Mesothelioma Chemotherapy Treatment Icon Chemotherapy This is the most common treatment for peritoneal mesothelioma. It is sometimes administered directly to the abdomen during surgery. Mesothelioma Radiation Treatment Icon Radiation This is the least invasive treatment option for peritoneal mesothelioma patients. Radiation may be delivered during surgery as well. Guide Book Covers OUR FREE MESOTHELIOMA GUIDE INCLUDES: 200+ Pages about your diagnosis 3 Books to improve your prognosis Wristbands to show your support SENT OVERNIGHT! Get your free guide Symptoms A patient with peritoneal mesothelioma may not experience symptoms early on. If symptoms are evident, they may be mistaken for other illnesses. One common symptom in many peritoneal mesothelioma patients is fluid pockets called ascites, which often cause the stomach region to bulge outward. Other symptoms include: Abdominal Pain Loss of Appetite Blood Clots Fatigue Fluid Buildup (Ascites) Nausea Abdominal Swelling Fever or Sweating Tissue Lumps in the Abdomen Anemia Seizures Bowel Problems In most cases, peritoneal mesothelioma does not spread to the lungs. It has been shown to spread to the other abdominal areas, such as ovaries, liver, or intestines. This metastasis often causes it to become discovered and sometimes misdiagnosed. Symptoms of stomach pains or ascites sometimes results in a misdiagnosis of hernias or a simple stomachache. Unlike pleural mesothelioma, peritoneal mesothelioma is most common in females between the ages of 51-59 years old. Men who are diagnosed with peritoneal mesothelioma are often veterans and those with occupational exposure to asbestos. Research suggests that peritoneal mesothelioma patients aged 60 and younger have a better survival rate. Peritoneal mesothelioma does not usually spread to the lymphatic system (lymph nodes) or blood stream. It usually metastasizes in large masses in the same areas where it originated. How Does Peritoneal Mesothelioma Develop? 1 Asbestos fibers are ingested. This can happen after being inhaled, coughed up, and then swallowed. 2 The body attempts to filter and remove them, but the sharp fibers can lodge into the lining of the abdomen (peritoneum). The fibers irritate the peritoneum and can cause genetic damage to cells. 3 Genetic damage can keep cells from receiving important signals about when to stop replicating. This causes unchecked cell division and the formation of a malignant tumor. It can take decades for this process to happen.